To find the percentage difference between two numbers, we first need to find the absolute difference between them. In this case, the absolute difference between 80 and 160 is 80 (160 - 80 = 80).

Next, we need to find the average of the two numbers. The average of 80 and 160 is (80 + 160) / 2 = 120.

Now, we can find the percentage difference by dividing the absolute difference by the average and multiplying by 100. So, the percentage difference between 80 and 160 is (80 / 120) x 100 = 66.67%.

This means that the second number (160) is 66.67% greater than the first number (80).