To find the percentage difference between two numbers, we first need to calculate the absolute difference between them. In this case, the absolute difference between 466 and 500 is 34.

Next, we need to find the average of the two numbers. The average of 466 and 500 is (466+500)/2 = 483.

Now, we can calculate the percentage difference by dividing the absolute difference by the average and multiplying by 100. So, the percentage difference between 466 and 500 is (34/483) x 100 = 7.04%.

Therefore, the percentage difference between 466 and 500 is 7.04%. This means that the difference between the two numbers is 7.04% of their average value.