To find the percentage difference between two numbers, we first need to find the absolute difference between them. In this case, the absolute difference between 372 and 250 is 122 (372 - 250 = 122).

Next, we need to find the average of the two numbers. The average of 372 and 250 is (372 + 250) / 2 = 311.

Now, we can calculate the percentage difference by dividing the absolute difference by the average and multiplying by 100. So, the percentage difference between 372 and 250 is (122 / 311) x 100 = 39.23%.

Therefore, the percentage difference between 372 and 250 is 39.23%. This means that the two numbers differ by 39.23% of their average value.