To find the percentage difference between two numbers, we first need to calculate the absolute difference between them. In this case, the absolute difference between 365 and 52 is 313 (365 - 52 = 313).

Next, we need to find the average of the two numbers. The average of 365 and 52 is (365 + 52) / 2 = 208.5.

Now, we can calculate the percentage difference by dividing the absolute difference by the average and multiplying by 100. So, the percentage difference between 365 and 52 is (313 / 208.5) x 100 = 150.15%.

This means that the second number (52) is 150.15% less than the first number (365). Alternatively, we can say that the first number is 150.15% greater than the second number.