To find the percentage difference between two numbers, we first need to find the absolute difference between them. In this case, the absolute difference between 350 and 273 is 77.

Next, we need to find what percentage of the original number the absolute difference represents. To do this, we divide the absolute difference by the original number (in this case, 350) and then multiply by 100 to get the percentage.

So, the percentage difference between 350 and 273 is:

(77/350) x 100 = 22%

This means that 22% of 350 is equal to the absolute difference between 350 and 273. In other words, if we subtract 22% of 350 (which is 77) from 350, we get 273.