To find the percentage difference between two numbers, we first need to calculate the absolute difference between them. In this case, the absolute difference between 245 and 49 is 196.

Next, we need to find the average of the two numbers. The average of 245 and 49 is (245+49)/2 = 147.

Now, we can calculate the percentage difference by dividing the absolute difference by the average and multiplying by 100. So, the percentage difference between 245 and 49 is (196/147) x 100 = 133.33%.

This means that the second number (49) is 133.33% less than the first number (245). Alternatively, we can say that the first number is 233.33% greater than the second number.