To find the percentage difference between two numbers, we first need to calculate the absolute difference between them. In this case, the absolute difference between 22 and 35 is 13.

Next, we need to find the average of the two numbers. The average of 22 and 35 is (22+35)/2 = 28.5.

Now, we can calculate the percentage difference by dividing the absolute difference by the average and multiplying by 100. So, the percentage difference between 22 and 35 is:

(13/28.5) x 100 = 45.61%

Therefore, the percentage difference between 22 and 35 is 45.61%. This means that 35 is 45.61% more than 22.