To find the percentage difference between two numbers, we first need to find the absolute difference between them. In this case, the absolute difference between 169 and 25 is 144 (169 - 25 = 144).

Next, we need to find the average of the two numbers. The average of 169 and 25 is (169 + 25) / 2 = 97.

Now, we can calculate the percentage difference by dividing the absolute difference by the average and multiplying by 100. So, the percentage difference between 169 and 25 is (144 / 97) x 100 = 148.45%.

This means that the second number (25) is 148.45% less than the first number (169). Alternatively, we can say that the first number (169) is 148.45% more than the second number (25).